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Reply To: Saturated and Simple Sugars Cause Hypothalmus Damage and Obesity?

Blog Forums Nutrition Saturated and Simple Sugars Cause Hypothalmus Damage and Obesity? Reply To: Saturated and Simple Sugars Cause Hypothalmus Damage and Obesity?


Thanks, Jman99! I thank you for stating your appreciation :)

But I wanted to both edit one of my comments above and clarify a couple things.

First, I’d like to edit my comment of the PUFA% in my previous post. I mis-stated the amount of PUFA above in the High Fat Diet.

I said the FAT CONTENT was >50% PUFA and so the TOTAL DIET was >30% PUFA. I mis-read this. The real numbers are that the FAT CONTENT is >30% PUFA, and so the TOTAL DIET is ~20% PUFA. Most of this is Linoelic acid, as I stated before. The ‘Scholarly Review’ looks at several trials, but the ones showing injury are using ‘lard’ which is now >30% PUFA. Once-upon-a-time, industrial lard was lower in PUFA and higher in saturated fat. That day is past.

Second, my friend who reads this blog (and my post here) but does not comment asked me in person about my post, and I wanted to clarify something by highlighting a couple sentences from the original Review abstract:

Quotes From Original Abstract

1. Excessive intake of certain macronutrients, such as simple carbohydrates and SFA, can lead to obesity and attendant metabolic dysfunction, also reflected in alterations in structural plasticity, and, intriguingly, neurogenesis, in some of these brain regions.

2. The present review draws together these observations and investigates whether PUFA may exert their attenuating effects on body weight through the stimulation of adult neurogenesis.

3. Exploration of the effects of nutraceuticals on neurogenic brain regions may encourage the development of new rational therapies in the fight against obesity.

My explanations:

1. By ‘SFA’ (saturated fatty acids), the authors mean diets high in lard from pigs fed soybeans and corn, which results in fat that is ~30% Linoleic acid, with a n6:n3 ratio of about 17. The Saturated Fat content of the High Fat Diet appears to be about 30%, or about 20% of total calories in the overall High Fat Diet.

2. By ‘PUFA’ (polyunsaturated fatty acids), the authors mean fish oils, with both EPA/DHA and straight DHA preparations used in various experiments resulting in the same result: attenuating (lessening) the damage of the High Fat Diet (the diet which, in reality, is high in linoleic acid n6)

3. As The Real Amy said, these authors clearly have the goal of patenting/selling a drug/supplement/protocol which, though the norm in medical research, strongly biases both the questions and answers of the analysis.

  • This reply was modified 10 years, 3 months ago by celticphoenix.