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MTHFR gene and mutations

Blog Forums Diseases and Conditions MTHFR gene and mutations

  • This topic has 6 replies, 2 voices, and was last updated 10 years ago by LB.
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  • #12165
    Wendywho
    Participant

    I’ve just read about this gene and how common mutations of it are. From what I’ve read, it can be implicated in many conditions. Anyone know much about it? I think the research is also somewhat new and so maybe many doctors know about it. From http://www.stopthethyroidmadness.com/mthfr/,
    The journal Molecular Psychiatry states that ?Schizophrenia-like syndromes, bipolar disorder, Parkinson’s disease, Alzheimer’s disease and vascular dementia have all been associated with one or more mutations of the MTHFR gene?. (2006;11, 352?360)

    From http://mthfr.net/
    “I believe the MTHFR gene mutation is a highly significant public health problem that is completely ignored. Yet, millions are suffering from pulmonary embolisms, addictions, fibromyalgia, miscarriages, schizophrenia, severe depression, cancer and autism to name a few.

    What do these conditions have in common?
    They all may be linked to a MTHFR gene mutation in the individual expressing these symptoms and health conditions.

    If we can prevent the turning on of the MTHFR gene mutation in unborn infants, how huge would that be? MASSIVE.

    If we can reduce mental illness, addictions, cancer and cardiovascular disease related deaths, how huge would that be? MASSIVE.”

    #12167
    Wendywho
    Participant

    Coincide – I just saw some comments mention MTHFR on today’s article about birth control pills. This morning I first read about MTHFR in some Amazon reviews and have been trying to look this afternoon.. I am very interested in how it defects in this gene could show up as mental disorders and brain fog.

    #12176
    LB
    Participant

    Hi Wendy

    I have a version of the MTHFR mutation. Mine apparently is the same as the one a lot of autistic kids have (compound heterozygous). My sister’s son is autistic, so I suppose there are a few of these mutations floating around in my family. My son has also tested positive for a variation of the mutation.

    An improved ability to detox heavy metals would probably explain why my own fogginess has decreased since starting supplementation a few months ago. My copper levels were really high before starting the regime, and they have reduced by 30% now.

    Good luck looking into this. It’s a really new area and most Drs don’t believe it’s worth learning about (from my experience).

    Lorien.

    #12204
    Wendywho
    Participant

    Thanks for your reply Lorien. I don’t have health insurance so am wondering if it is worth it to save up to get those tests or do you think it would be ok to just supplement as if I did have a defect? I think I’ve had depression and anxiety since the day I was born and both seem to run on both sides of my family. My kids seem to have a lot of anxiety too.

    #12205
    Wendywho
    Participant

    I have to amend something – there is a woman in my social circle who has breast implants (she used to be a stick), dresses sexy and works out an insane amount of time – now she is built and gets whistled at… She is well like but she was well liked too before the implants and putting on lots of muscles, though she probably wasn’t whistled at.

    #12206
    Wendywho
    Participant

    Oops – i meant the above post to go somewhere else!

    #12213
    LB
    Participant

    You could probably go to mthfr.net and read some of the articles Ben Lynch has written and go ahead and take the supplements and see if they make you feel better I guess?

    Methylfolate in particular can have strong reactions, so I would have been a bit reluctant to experiment on my 3 year old without my Dr’s guidance. My son has
    been taking a really low dose of the supplements for about 2 weeks now though and I have to say he’s a lot calmer, happier, nicer and hungrier than he was beforehand. It could be a coincidence though! I’ve got my fingers crossed.

    There’s a lot of sensible info at mthfr.net.

    Good luck.

    Cheers, Lorien

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