I used tianeptine for a couple of years when I was at my sickest, and if you do a forum search, you’ll find a thread where I talk about my experiences in detail. Long story short, I found it astonishingly useful for several months, but it gradually lost potency until finally I gave it up.
But even at its best, it wasn’t fixing the problem, just masking it. That’s okay, because sometimes you need a bandage, but I think non-pharma options may be necessary for fundamental health changes.